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Casey L. Moulson, PhD |
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instructor in medicine Renal Division (314) 362-8234
tel web: Personal Weblink
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RESEARCH INTEREST Cellular uptake of fatty acids requires facilitated transport through several different families of proteins. One family is the family of 6 fatty acid transport proteins (FATPs). The most widely expressed of those is FATP4. Our lab is interested in the role of FATP4 in two organs with very high expression of FATP4-the skin and small intestine. We have genetically altered mice carrying mutations in FATP4 and mice that express FATP4 only in the skin. We are using these mice to investigate the function of FATP4 in skin development and its involvement in intestinal uptake of dietary fatty acids. SELECTED PUBLICATIONS Moulson CL, Go G, Gardner JM, van der Wal AC, Sillevis Smitt JH, van Hagen JM, and Miner JH. Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy. J Invest Derm. 2005;(in press).
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